Eppendorf, a leading life science company, has announced a series of       complimentary seminars and luncheons on the west coast and the east       coast featuring topics such as stem cells, perfusion and scalability.

Scale-up and suspension adaptation of Mesenchymal and Induced       Pluripotent Stem Cells (MSCs and iPSCs) are currently the focus of       intense study. Although successful expansion of Mesenchymal Stem Cells       (MSCs) in vitro has been well established, the large-scale       production of MSCs remains a bottleneck. Join Eppendorf as they       demonstrate a successful large scale bioprocess application of       adipose-derived mesenchymal stem cells (AdMSCs) in an industrial       single-use bioreactor vessel at 3.75 L scale (working volume).

Biosimilars are a fast-growing segment of the biopharmaceutical market.       Using a CHO cell line expressing a human MAb, we will compare three       methods of MAb production using the new BioFlo 320 bioprocess control       station. The common batch and fed-batch protocols are discussed, as well       as an alternating tangential flow filtration perfusion.

The ultimate goal for process development is the realization of       large-scale commercial production. Currently, the scale-up of       fermentation processes, which is critical to the success of industrial       fermentation for bioproduction, are receiving a lot of attention. The       fermentation scale-up from benchtop (1 L to 10 L scale) to       pilot/production scale (> 100 L) is the important step for effective       production of biologicals, including small proteins in the       biopharmaceutical market. Join us as we investigate the scale-up       capabilities of Eppendorf fermentation systems from small to large scale.

Please see below for the locations and topics to be presented at each       location.

San Francisco Area, CA - Tuesday, September 22, 2015
Topics:       Achieving Scalability of hMSC in Single-Use Vessels and Scale-up in       Fermentation Systems
Click       here for online registration for the San Francisco Seminar

San Diego Area, CA - Thursday, September 24, 2015
Topics:       MAb Production Comparing Batch, Fed-Batch and Perfusion Protocols, and       Scale-up in Fermentation Systems
Click       here for online registration for the San Diego Seminar

Research Triangle Park (RTP) Area, NC - Tuesday, October 6, 2015
Topics:       MAb Production Comparing Batch, Fed-Batch and Perfusion Protocols, and       Scale-up in Fermentation Systems
Click       here for online registration for the RTP Seminar

Gaithersburg Area, MD - Thursday, October 8, 2015
Topics:       MAb Production Comparing Batch, Fed-Batch and Perfusion Protocols, and       Scale-up in Fermentation Systems
Click       here for online registration for the MD Seminar

While attendance is free for these informative seminars, space is       limited. As such, please register today to participate in these events.

If you are interested in attending a similar seminar in your area please       email Carol Stanton at stanton.c@eppendorf.com       and you will be notified when a seminar is scheduled in your region.

About Eppendorf AG:

Eppendorf is a leading life science company that develops and sells       instruments, consumables, and services for liquid handling, sample       handling, and cell handling in laboratories worldwide. Its product range       includes pipettes and automated pipetting systems, dispensers,       centrifuges, mixers, spectrometers, and DNA amplification equipment as       well as ultra-low temperature freezers, fermentors, bioreactors, CO2       incubators, shakers, and cell manipulation systems. Consumables such as       pipette tips, test tubes, microliter plates, and disposable bioreactors       complement the range of highest-quality premium products.

Eppendorf products are most broadly used in academic and commercial       research laboratories, e.g., in companies from the pharmaceutical and       biotechnological as well as the chemical and food industries. They are       also aimed at clinical and environmental analysis laboratories,       forensics, and at industrial laboratories performing process analysis,       production, and quality assurance.

Eppendorf was founded in Hamburg, Germany in 1945 and has about 2,850       employees worldwide. The company has subsidiaries in 25 countries and is       represented in all other markets by distributors.